Recommending 400-600 milligrams of flavanols per day to support cardiometabolic health addresses the global health challenge of cardiovascular disease, a leading cause of morbidity and mortality worldwide. is intended for
Catherine Kwik-Uribe, Ph.D., Vice President of Science & Regulatory Affairs, Applied Science & Nutrition at Mars Edge, said the advisory issued last week (October 11) is exciting for the industry. .
“For more than 20 years, scientists and others on Mars have studied flavanols and how they benefit human health. This recommendation is an important milestone in this emerging nutritional field. .na
“This recommendation will stimulate greater interest and awareness of the important role flavanols can play in health and nutrition, from health professionals to consumers, and may soon be fully included in global dietary guidelines.” I hope to foster some conversation.”na
She adds that she finds the recommendations particularly impressive because they focus on promoting health rather than preventing deficiencies, which is the most common approach when making recommendations for things like vitamins and minerals.
The letter of recommendation reads: “There is moderate evidence in the literature supporting cardiometabolic protection from flavan-3-ol intakes in the range of 400 to 600 mg per day. , total cholesterol, HDL-cholesterol, and insulin/glucose kinetics) had the strongest evidence. na
“It should be noted that this is a food-based guideline and not a recommendation for flavan-3-ol supplements. A comprehensive evaluation of the available data indicates that the evidence gaps identified here can inform scientists and thereby guide future randomized clinical trials.”na
These recommendations have been implemented relatively quickly given the recent arrival of flavanols on the health and nutrition radar, says Dr. Kwik-Uribe.
“It’s amazing considering how quickly we got to the official recommendation.” She told NutraIngredients, “While our understanding of vitamins and minerals and their importance to health has been understood for over 50 years, flavanols have long been known to be found in the foods we eat. It was only recently that it entered the nutrition scene.”na
scientific discovery
Over the past decades, hundreds of human intervention studies using flavanols have led to significant advances in analysis, global food composition databases, and comprehensive studies on the absorption and metabolism of specific flavanols.
For example, COSMOS is the first and largest randomized controlled trial of flavanols and cardiovascular health published this year.
A recent publication on the European Prospective Cancer Study (EPIC) Norfolk cohort that examined the relationship between flavanol intake and blood pressure found that the top 10% of the population had an average flavanol intake of 270 mg/day (range 146-618 mg/day). Day). In this same study, using validated biomarkers of flavanol intake, participants with the highest flavanol intake had systolic blood pressure that was 2–2.5 mmHg lower than those with the lowest intake. It’s important to note (similar differences are seen in diastolic blood pressure) – a fairly large drop in blood pressure.
Dr. Kwik-Uribe says the new recommendations fairly reflect the available science.
“Given the available evidence on flavanols, including the recently published significant results of the COSMOS trial, this recommendation is consistent with the evidence and very realistic from a dietary perspective. This is a great start, and while the recommendations will evolve over time, both in specificity and recommendations on how to achieve levels, current recommendations are more likely to increase awareness of the health benefits of flavanols. It’s a big step.na
“The good news is that flavanols are found in a variety of foods, including teas, berries, pears, and nuts, so consumers can easily increase their intake of flavanols by making small changes to their diet.” increase.”na
mars edge
Mars Edge, a division of Mars, Incorporated, is dedicated to human health and wellness through targeted nutrition.
The business creates new ways to manufacture, market, sell and distribute new consumer product solutions and services that address malnutrition, personalized nutrition and healthy aging.
The team is currently working on bioactive substances, especially their Dietary Supplements COCOAVIA leverages over 20 years of cocoa flavanol research to create evidence-based products that support healthy blood flow.
We are also building a global personalized nutrition business, beginning with our partnership with Foodspring, one of Europe’s largest and fastest growing direct-to-consumer nutrition companies.
sauce: nutritional advancement na
https://doi.org/10.1093/advances/nmac105
“Flavan-3-ols and cardiometabolic health: Guideline recommendations from the Academy of Nutrition and Dietetics”na
Author: KM Crowe-White, et al.
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